Richard (Rick) Barry has served as a Director since June 2021 and was appointed Chief Executive Officer in September 2024. Mr. Barry served as Executive Chairman of the Board beginning July 2024 until his appointment as Chief Executive Officer. Since June 2015, Mr. Barry has also served as Director of Sarepta Therapeutics, Inc., (Nasdaq: SRPT). Mr. Barry has extensive experience in the investment management business. He was a founding member of Eastbourne Capital Management LLC, and served as a Managing General Partner and Portfolio Manager from 1999 to its close in 2010. Prior to Eastbourne, Mr. Barry was a Portfolio Manager and Managing Director of Robertson Stephens Investment Management. Mr. Barry holds a Bachelor of Arts from Pennsylvania State University.

James W. Kupiec, M.D. joined the Company in January 2021 as Chief Clinical Development Officer and has served as our Chief Medical Officer since December 2022. Dr. Kupiec joined the Company after three decades of drug development experience at Pfizer, Sanofi and Ciba-Geigy. Dr. Kupiec previously served as VP, Global Clinical Leader for Parkinson’s Disease and Clinical Head of the Neuroscience Research Unit for Pfizer, Inc., in Cambridge, MA. He joined Pfizer in 2000 after seven years with Sanofi, and two years with Ciba-Geigy Pharmaceuticals. During his 17-year career at Pfizer, Dr. Kupiec had extensive governance, business development, alliance and leadership responsibilities. Dr. Kupiec earned his BS with Honors in Biochemistry at Stony Brook University and his MD from the Albert Einstein College of Medicine. He completed his residency training at the Strong Memorial Hospital, University of Rochester School of Medicine, and is certified by the American Board of Internal Medicine. He served as an investigator on many clinical trials before joining the pharmaceutical industry.

Chris Cook joined SAVA as Senior Vice President and General Counsel in October 2022. He previously served as the Global Head of Litigation and Government Investigations for Alcon, a publicly traded medical device and pharmaceutical company, as well as the Vice President and division General Counsel for Walmart Central America in San Jose, Costa Rica. Chris also spent seventeen years at Jones Day, where he was a litigation partner in the firm's Washington, DC and Chicago offices. Chris served as an Assistant United States Attorney in Chicago and graduated from Harvard Law School.

Eric Schoen has served as SAVA’s Chief Financial Officer since 2018. Prior to joining the Company, Mr. Schoen served as Vice President, Senior Vice President, Finance and Chief Accounting Officer of Aspira Women’s Health Inc. (formerly Vermillion, Inc.), a publicly-held women’s health company, from 2011 to 2017. Mr. Schoen also began his career and spent nine years with PricewaterhouseCoopers in the audit and assurance, transaction services and global capital markets practices.

Mike Zamloot has 35 years of pharmaceutical industry experience with multinational firms and development stage biopharmaceutical companies. He has held his current position with Cassava Sciences since 2000, and has responsibility for all aspects of Pharmaceutical Development, Quality and Supply Chain Management. Mike holds a BS degree in Chemical Engineering with honors from the New Jersey Institute of Technology and is an inventor on more than 25 patents.

Ben Thornton has over 30 years experience in leading research and development teams in large pharma (Johnson & Johnson) and start up biotechnology companies (GeneMedicine, Apovia) translating basic science to the clinical setting. He has held his current position with Cassava Sciences since 2005. Ben holds a PhD in Molecular Biology from the University of Texas M.D. Anderson School of Biomedical Sciences and was a post-doctoral fellow at the Roche Institute of Molecular Biology. He is currently a Trustee of The Torrey Pines Institute for Molecular Sciences.

Mike Marsman, PharmD has worked with SAVA as an employee or consultant since 2004. He has over 35 years providing leadership for Regulatory Affairs and Quality Assurance with both multinational and development stage pharmaceutical companies, including Impax, Millennium, COR Therapeutics, Liposome Technology, and Syntex. Dr. Marsman achieved multiple FDA drug approvals prior to joining Cassava Sciences.